• B-hRETN mice

    C57BL/6-Retntm1(RETN)Bcgen/Bcgen • 112361

    B-hRETN mice

    Product nameB-hRETN mice
    Catalog number112361
    Strain nameC57BL/6-Retntm1(RETN)Bcgen/Bcgen
    Strain backgroundC57BL/6
    NCBI gene ID (Human)
    AliasesADSF; RENT; RSTN; XCP1; FIZZ3; RETN1

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    • Targeting strategy
    • Phenotypic analysis

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      发表文章

        Targeting strategy

        Gene targeting strategy for B-hRETN mice. The exons 1~5 of mouse Retn gene that encodes the full-length protein was replaced by human RETN exons 1~4 in B-hRETN mice.

        Protein expression analysis

        Strain specific resistin expression analysis in homozygous B-hRETN mice by ELISA. Serum were collected from wild-type mice C57BL/6 mice (+/+) and homozygous B-hRETN mice (H/H), and analyzed by ELISA with species-specific resistin ELISA kit. Mouse resistin was detectable in wild-type mice (A). Human resistin was exclusively detectable in homozygous B-hRETN mice but not in wild-type mice (B).

        * When publishing results obtained using this animal model, please acknowledge the source as follows: The animal model [B-hRETN mice] (Cat# 112361) was purchased from Biocytogen.
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