• B-hNRP1 mice

    C57BL/6-Nrp1tm1(NRP1)Bcgen/Bcgen • 111330

    B-hNRP1 mice

    Product nameB-hNRP1 mice
    Catalog number111330
    Strain nameC57BL/6-Nrp1tm1(NRP1)Bcgen/Bcgen
    Strain backgroundC57BL/6
    NCBI gene ID (Human)
    AliasesNP1; NRP; BDCA4; CD304; VEGF165R

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    • Phenotypic analysis

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        Protein expression analysis in Treg cells

        Strain specific NRP1 expression analysis in homozygous B-hNRP1 mice by flow cytometry. Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hNRP1 mice (H/H), and analyzed by flow cytometry with species-specific anti-NRP1 antibody. Mouse NRP1 was detectable in wild-type mice. Human NRP1 was exclusively detectable in homozygous B-hNRP1 but not in wild-type mice.

        Protein expression analysis in CD4+ T cells

        Strain specific NRP1 expression analysis in homozygous B-hNRP1 mice by flow cytometry. Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hNRP1 mice (H/H), and analyzed by flow cytometry with species-specific anti-NRP1 antibody. Mouse NRP1 was detectable in wild-type mice. Human NRP1 was exclusively detectable in homozygous B-hNRP1 but not in wild-type mice.

        * When publishing results obtained using this animal model, please acknowledge the source as follows: The animal model [B-hNRP1 mice] (Cat# 111330) was purchased from Biocytogen.
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